![]() ![]() However, the production of amyloid beta exceeds the clearance from the body in a diseased condition, leading to target proteins attain toxicity following their transition from a α-helix to a β-sheet form. Aβ has physiological importance and is mainly produced by amyloidogenic metabolism of amyloid precursor protein, by sequential action of β- and γ-secretases, leading to the liberation of peptide between 39 and 42 amino-acid residues. One of the pathological events in the progression of AD is the conformational changes and misfolding of the amyloid beta protein(Aβ), concentrated in the synapses of neurons. MCAT Chemistry/Biochemistry Practice Passage #1Īlzheimer’s Disease(AD) is a neurodegenerative disease. With that being said, let’s dive into sample MCAT chemistry/biochemistry practice questions and answers! Remember to try the passages and questions by yourself first, without looking at the expert responses we provided. ![]() For these reasons, this section on MCAT tests your basic knowledge about necessary relevant topics, so that you not only look at the disease but can also understand the disturbance in the biochemical make-up leading to that. How does the body work? How do proteins fold? How do enzymes carry out basic reactions like digestion, breathing, and so on? Why does lung capacity depend on partial pressure of oxygen and carbon dioxide? How many milligrams of dose should be given to a patient based on his/her weight? As you see, to treat a patient, you need to have some basic knowledge about chemical reactions and biochemical processes, as well as MCAT chemistry equations and other high-yield MCAT topics. Why it is so important to have conceptual understanding of MCAT chemistry and biochemistry topics for your MCAT prep? As a healthcare professional, depending on your medical specialty, you will be working with patients, trying to understand the root cause of their health issues, administering drugs, anesthesia doses, and so on. ![]()
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